方法

可见性研究使用84位幽门螺杆菌既往感染患者的EGC白光和LCI两类图像。使用可见性评分和色差（CD）值评估内镜可见度。为了分析漏诊率，我们使用了70位幽门螺杆菌根除后患者的白光和LCI图像的录制视频库，其中19位有早期胃癌（EGC）。使用相同的方案绘制整个胃以完成内镜筛查。六名内镜医师随机查看视频。比较不同方式之间EGC的漏诊率。

Methods: The visibility study used two images, one each with WLI and LCI, from 84 consecutive EGC after H. pylori eradication. Endoscopic visibility was evaluated using a visibility score and color difference (CD) value. To analyze miss rates, we studied a library of recorded videos using both WLI and LCI for 70 other consecutive patients after H. pylori eradication, among whom 19 had EGC. Endoscopic screening was done using the same protocol to map the entire stomach. Six endoscopists reviewed the videos in a randomized order. Miss rates of EGC were compared among the modalities.

结果

LCI组的平均（标准差）可视化评分显著高于白光组（3.19 ± 0.84 vs 2.52 ± 0.98, P < 0.001），平均CD值也是如此（26.3 ± 9.1 vs 13.6 ± 6.3, P < 0.001）。LCI组六名内镜医师的漏诊率显著低于白光组（30.7% vs 64.9%, P < 0.001）。专家和实习内镜医师使用LCI的结果明显好于白光组。  

Results: Mean [(±standard deviation) visibility scores with LCI were significantly higher than those with WLI (3.19 ± 0.84 vs 2.52 ± 0.98, P < 0.001), as were mean CD values (26.3 ± 9.1 vs 13.6 ± 6.3, P < 0.001). Miss rates of the six endoscopists were significantly lower with LCI than with WLI (30.7% vs 64.9%, P < 0.001). Both expert and trainee endoscopists had significantly better results with LCI than with WLI.