目的

我们的目的是研究联动成像技术(LCI)与白光内镜(WLE)检测胃肠化生(GIM)的能力。107名接受上消化道内镜检查的参与者被纳入研究。在WLE内镜下，对任何可疑的黏膜异常改变进行活检。在LCI内镜下，我们检测了斑片状薰衣草色(PLC)的特定颜色特征是否为GIM的病理标志。随机对既没有PLC也没有怀疑病变的参与者进行活检。通过组织学和内镜检查的比较，评估LCI和WLE的检测能力。共有41名参与者患有组织学GIM。LCI对GIM的总诊断率为79.44%，高于WLE的40.19% (P < 0.001)。此外，有针对性的活检显示LCI检测GIM的能力显著增加(P < 0.001)。LCI观察到胃黏膜PLC，可指导内镜活检，提高GIM的检出率。因此，LCI可以成为检测GIM的一个很好的工具。

Aims: We aimed to investigate the ability of linked color imaging (LCI) versus white light endoscopy (WLE) to detect gastric intestinal metaplasia (GIM). One hundred and seven participants who underwent upper gastrointestinal endoscopy were included. Under WLE endoscopy, biopsies were performed on any suspected abnormal mucosal changes. Under LCI endoscopy, we tested whether the specific color feature of patchy lavender color (PLC) pathologically indicated GIM. Biopsies were randomly performed in participants who had neither PLC nor suspected lesions. The detection abilities of LCI and WLE were assessed by comparison of histological and endoscopic findings. A total of 41 participants had histological GIM. The total diagnostic accuracy rate for GIM by LCI was 79.44%, higher than that of WLE (40.19%) (P < 0.001). Moreover, LCI with targeted biopsies showed a significantly increased ability to detect GIM (P < 0.001). PLC observed in the gastric mucosa on LCI can guide endoscopic biopsies and increase the detection rate of GIM. Thus, LCI could be a good tool for detecting GIM. ClinicalTrials.gov Identifier: ChiCTR-DDD-17011326).