联动成像技术（LCI）是一种用于增加色彩对比度的新型内镜系统。由于LCI不会降低管腔亮度，它能改善结肠肿瘤检测。然而，LCI改善结肠息肉可见度的程度尚未确定。在2016年12月至2017年5月期间，接受全结肠检查的患者被连续招募到这项回顾性单中心研究中。对于识别出的每个息肉，评估从同一病变及其周围黏膜的白光（WL）图像、蓝光成像（BLI）和LCI获得的图像。使用CIELAB色彩空间定量计算非放大图像中每个病变与其周围黏膜之间的色差（ΔE）。该色彩空间根据比色值定义颜色感知，并在白光、BLI、LCI和染色内镜之间进行比较。还评估了放大图像中血管和非血管区域之间的ΔE。在纳入本研究的64名患者中，分别评估了113个和95个息肉的非放大和放大（x80）图像。与白光和BLI相比，LCI和染色内镜检查增强了ΔE。LCI也增强了肿瘤病变的ΔE。在放大图像中，与白光相比，BLI和LCI显著增加了血管和非血管区域之间的ΔE。L*表示的发光亮度不受LCI影响；但是，与白光和LCI相比，BLI的发光亮度减少了。这些结果表明，LCI增强了对结肠肿瘤的检测，且不妨碍管腔亮度。我们建议常规使用LCI检测结肠息肉，使用BLI放大观察LCI检测到的结肠息肉。

Abstract: Linked color imaging (LCI) is a novel endoscopic system used to increase color contrast. As LCI does not decrease luminal brightness, it may improve the detection of colonic neoplasms. However, the extent to which LCI improves the visibility of colonic polyps has not yet been determined. Between December 2016 and May 2017, patients who received total colonoscopy were consecutively recruited into this retrospective, single‑center study. For each polyp identified, images obtained from white light (WL) imaging, blue laser imaging (BLI), and LCI of the same lesion and its surrounding mucosa were evaluated. The color differences (ΔE) between each lesion and its surrounding mucosa in non‑magnified images were computed quantitatively using the CIELAB color space, which defines color perception according to colorimetric values, and compared among WL, BLI, LCI, and chromoendoscopy. The ΔE between the vessel and non‑vessel areas in magnified images was also assessed. Of the 64 patients who were incorporated into this study, non‑magnified and magnified (x80) images from 113 and 95 polyps, respectively, were assessed. The ΔE was intensified by LCI and chromoendoscopy compared with WL and BLI. The ΔE of neoplastic lesions was also intensified by LCI. In magnified images, BLI and LCI significantly increased the ΔE between the vessel and non‑vessel areas compared with WL. Luminal brightness, indicated by L*, was not impaired by LCI; however, was reduced by BLI compared with WL and LCI. These results suggest that LCI enhanced the detection of colonic neoplasms without impairing luminal brightness. We propose the routine use of LCI for colonic polyp detection and BLI for magnifying observations of colonic polyps detected by LCI.