方法

招募277名接受高分辨率白光胃镜检查的患者，再用LCI模式检查以进行EGGIM评估。用LCI模式进行整个胃黏膜检查。记录胃窦、胃体的小弯和大弯以及切迹五个区域的图像。对于每个区域，0分（无GIM）、1分（局部GIM，≤30%的区域）和2分（广泛GIM，>30%的区域）归纳为10期。如果根据内镜检查结果怀疑GIM，则进行有针对性的活检；如果GIM不明显，则根据悉尼系统进行随机活检以评估基于肠化的胃炎评价（OLGIM）。

Methods: Two hundred and seventy-seven patients who underwent high-resolution white-light gastroscopy followed by LCI for EGGIM estimation were included. LCI was performed for the entire mucosa, and images of five areas each were recorded from the lesser and greater curvatures of the antrum and corpus, and for the incisura. For each area, scores of 0 (no GIM), 1 (focal GIM, ≤30% of the area), and 2 (extensive GIM, >30% of the area) were attributed for 10 points. If GIM was suspected based on endoscopy findings, targeted biopsies were performed; if GIM was not evident, random biopsies were performed according to the Sydney system to estimate the operative link on GIM (OLGIM).

结果

分别有136、70、37、28和 6名患者的GIM评估为OLGIM 0、I、 II、 III和IV。OLGIM III/IV诊断，受试者工作特性曲线下面积为0.949（95% CI 80.3%–99.3%）。EGGIM 4期的敏感性和特异性分别为94.12% （95% CI 80.3%–99.3%）和 86.42% （95% CI 81.5%–90.5%），被 确认为识别OLGIM III/IV患者的最佳分界值。

Results: GIM was staged as OLGIM 0, I, II, III, and IV in 136, 70, 37, 28, and 6 patients, respectively. For OLGIM III/IV diagnosis, the area under the receiver operating curve was 0.949 (95% CI 0.916–0.972). EGGIM of 4, with sensitivity and specificity of 94.12% (95% CI 80.3%–99.3%) and 86.42% (95% CI 81.5%–90.5%), respectively, was determined the best cut-off value for identifying OLGIM III/IV patients.